lymphatic system that includes fluid and lymph nodes that help our bodies to work efficiently, and to fight germs. There are hundreds of lymph nodes throughout the body, including in the chest, neck, armpit, groin, pelvis, and along the gut.
There are two main types of lymphocyteslymphocytes, also called white blood cells, in the lymphatic system. These are called:
In lymphomas, healthy lymphocytes transform into cancerous ones and begin to divide out of control. Lymphomas can involve either B cells or T cells and begin and travel almost anywhere in the body
Mantle cell lymphoma affects mostly men over the age of 60.
The disease is called “mantle cell lymphoma” because the tumor cells originally come from the outer edge of the lymph nodeslymph nodes called the “mantle zone.”
Patients with MCL may respond well to treatment once the disease is diagnosed, but within a few years, the disease may return after treatment. This means patients have relapsed MCL.
Patients may also have refractory MCL. Refractory MCL means that the disease does not respond to treatment.
The lymphatic system includes the tissues and organs that make, store, and carry the white blood cells that fight infections and other diseases. These include the bone marrow, spleen, thymus, and lymph nodes, as well as lymphatic vessels that spread throughout the body.
Lymphocytes are a type of white blood cells that are part of the immune system.
B lymphocytes produce antibodies that help fight invading bacteria, viruses, and toxins in the body.
T lymphocytes destroy the body’s own cells that have been taken over by viruses or have developed into cancer.
Cancer is the name for a collection of diseases in which some of the body’s cells begin to divide without stopping and spread into surrounding tissues.
Hodgkin lymphoma is a type of cancer of the immune system marked by the presence of a specific kind of cell called a Reed-Sternberg cell.
Non-Hodgkin lymphoma is a term that describes a large group of different types of lymphocyte cancers. Mantle cell lymphoma is a type of non-Hodgkin lymphoma.
Lymph nodes are small structures in the body that are part of the immune system. Lymph nodes contain lymphocytes that help the body fight infection and diseases.
These are not all the possible side effects of CALQUENCE. Call your doctor for medical advice about side effects.
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What is CALQUENCE?
CALQUENCE is a prescription medicine used to treat adults with mantle cell lymphoma (MCL) who have received at least one prior treatment for their cancer.
It is not known if CALQUENCE is safe and effective in children.