What You Need to Know About CALQUENCE® (acalabrutinib)

For adults with mantle cell lymphoma (MCL) who have received at least one prior treatment for their cancer.

CALQUENCE & MCL

CALQUENCE & MCL

A treatment option for adults with mantle cell lymphoma who have received at least one prior treatment for their cancer. In a clinical study of 124 patients taking CALQUENCE® (acalabrutinib), 80% responded, meaning radiographic and other tests showed that their cancer reduced in size and did not spread.

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TAKING CALQUENCE

TAKING CALQUENCE

Dosing information to help you stay on track with treatment. Take CALQUENCE® (acalabrutinib) twice daily, about every 12 hours, for example, 1 capsule in the morning and 1 at night.

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SUPPORT & RESOURCES

SUPPORT & RESOURCES

Throughout your treatment with CALQUENCE® (acalabrutinib), education and support can help you every step of the way. Enroll now for CALQUENCECares.

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IMPORTANT SAFETY INFORMATION

CALQUENCE may cause serious side effects, including:

  • Bleeding problems (hemorrhage) may happen during treatment with CALQUENCE, and can be serious. Your risk of bleeding may increase if you are also taking a blood thinner medicine. Tell your healthcare provider if you have any signs or symptoms of bleeding, including:
    • blood in your stools or black stools (looks like tar)
    • pink or brown urine
    • unexpected bleeding, or bleeding that is severe or you cannot control
    • vomit blood or vomit that looks like coffee grounds
    • cough up blood or blood clots
    • dizziness
    • weakness
    • confusion
    • change in your speech
    • headache that lasts a long time
  • Infections. Infections can happen during treatment with CALQUENCE. These infections can be serious and may lead to death. Tell your healthcare provider right away if you have fever, chills, or flu-like symptoms.
  • Decrease in blood cell counts. Decreased blood counts (white blood cells, platelets, and red blood cells) are common with CALQUENCE, but can also be severe. Your healthcare provider should do monthly blood tests to check your blood counts.
  • Second primary cancers. New cancers have happened in people during treatment with CALQUENCE, including cancers of the skin. Use sun protection when you are outside in sunlight.
  • Heart rhythm problems (atrial fibrillation and atrial flutter) have happened in people treated with CALQUENCE. Tell your healthcare provider if you have any of the following signs or symptoms:
    • your heartbeat is fast or irregular
    • feel lightheaded or dizzy
    • pass out (faint)
    • shortness of breath
    • chest discomfort

The most common side effects of CALQUENCE include:

  • headache
  • diarrhea
  • tiredness
  • muscle aches
  • bruising

These are not all the possible side effects of CALQUENCE. Call your doctor for medical advice about side effects.

You may report side effects related to AstraZeneca products by clicking here.

What is CALQUENCE?

CALQUENCE is a prescription medicine used to treat adults with mantle cell lymphoma (MCL) who have received at least one prior treatment for their cancer.

It is not known if CALQUENCE is safe and effective in children.

Please see complete Prescribing Information including Patient Information.